Baclofen’s action on the GABA receptors in the brain may help lessen cravings and withdrawal symptoms for alcohol. It may also help people remain abstinent from alcohol. More research is needed to find out how effective baclofen is in the treatment of alcoholism. Baclofen has been a huge success in curving alcohol cravings, but what are the benefits and risks for those struggling with alcohol abuse? As the baclofen dose is titrated up, the pattern of cravings and drinking will guide how much the baclofen dose needs increasing. This regime is not advised in the frail, isolated or frequently falling patient with a constant high alcohol intake. Detailed Baclofen dosage information for adults and children. Includes dosages for Spasticity, Cerebral Spasticity and Spinal Spasticity; plus renal, liver and dialysis adjustments. Results: The patient reported dramatic reduction in cravings for and preoccupation with alcohol. Conclusions: High-dose baclofen therapy was associated with complete and prolonged suppression of symptoms and consequences of alcohol-dependence. Suppression of symptoms of alcohol dependence This gives alcohol addicted patients confidence that the baclofen can help them and encourages them to stick with the titrating of the baclofen dose up until they get to the needed dose to suppress their cravings. User Reviews for Baclofen to treat Alcohol Withdrawal. Also known as: FIRST Baclofen, Lioresal, Lioresal Intrathecal, Gablofen. The following information is NOT intended to endorse drugs or recommend therapy. Twenty patients did not increase the dose of baclofen as much as they should have because they could not tolerate the side-effects above a certain dose (these patients belonged to the “at medium risk” and “at high risk” categories). Baclofen’s potential effects on dopamine and GABA may possibly redirect the domino-like effects that occur when cocaine enters the brain. Supportive Measures Because of the unforgiving nature of cocaine addiction, even an effective medication treatment requires additional supports to be in place in order for you to have a successful recovery. Baclofen and Alcohol Addiction. Studies have shown that baclofen can reduce alcohol cravings and withdrawal symptoms. One 2018 review of research detailed how baclofen affected the alcohol consumption of animals.